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How to get from Medellín to Cartagena, Colombia

Cartagena is well connected with Medellín. You can get from Medellín to Cartagena by bus, private transfer, flight, or rental car.

Welcome to Cartagena, a vibrant Colombia’s Caribbean coast city that promises a captivating blend of history, culture, and breathtaking landscapes!

Prepare to be enchanted as you explore the winding streets of the Old Town, adorned with colorful colonial buildings and overflowing with tales of Spanish conquests and pirate legends.

Immerse yourself in the rhythmic beats of salsa music filling the air, urging you to dance with the locals in lively plazas. And when the sun begins its descent, there’s no better way to embrace the magical Cartagena than aboard our Sunset Cruise with Open Bar.

Book your spot on our Sunset Cruise with Open Bar today and create memories that will linger in your heart long after the sun has set on this unforgettable Colombian experience.

Join us and embark on a journey where dreams become a reality amidst the beauty of Cartagena’s sunsets!

Traveling between Medellín and Cartagena is easy, and you can choose between a bus, private transfer, flight, and rental car.

Check our guide for the best options to travel from Medellín to Cartagena.

How far is Cartagena from Medellín?

The distance from Medellín to Cartagena is 398.1 miles or 640.6 kilometers.

It takes about 12 hours to travel from Medellín to Cartagena.

Transportation Options from Medellín to Cartagena

The following table outlines all transportation options from Medellín to Cartagena:

MethodTravel timePrice
Bus from Medellín to Cartagena14-16 hoursUSD 70-USD 96
Private Transfer from Medellín to CartagenaCustom TimeUSD 213-USD 583
Flight from Medellín to Cartagena1 hour 15 minutesUSD 71-USD 102
Rental Car~12 hours

Getting to Cartagena from Medellín

1. Bus from Medellín to Cartagena

Journey Duration: 14-16 hours

When traveling from Medellín to Cartagena, a coach bus or luxury bus is one of the most convenient and comfortable transportation options available.

These buses provide a hassle-free journey, allowing you to sit back, relax, and enjoy the scenic route as you make your way between these two vibrant cities!

Coach buses are a popular choice for travelers seeking an affordable yet comfortable mode of transportation. Equipped with spacious seating and ample legroom, these buses offer passengers of all ages a comfortable journey. 

With professional drivers at the helm, you can rest assured that safety is a top priority throughout your journey.

Medellín to Cartagena Coach Bus Schedule

Departure TimeArrival TimeDurationPrice per Person
05:30 AM09:10 PM15 hours 40 minutesUSD 70Book Now 3 E1661788865313
05:30 PM09:10 AM15 hours 40 minutesUSD 70Book Now 3 E1661788865313
08:15 PM11:55 AM15 hours 40 minutesUSD 70Book Now 3 E1661788865313
10:30 PM02:10 PM15 hours 40 minutesUSD 70Book Now 3 E1661788865313

For those who prefer a touch of luxury during their travels, luxury buses are the way to go.

These buses take comfort to the next level, featuring plush, reclining seats and additional amenities such as onboard entertainment systems and complimentary Wi-Fi. 

The luxury buses also provide enhanced services, including onboard restrooms and refreshments, ensuring a truly indulgent travel experience.

Both coach and luxury buses offer convenient departure and arrival times, allowing you to easily plan your itinerary.

In addition, they typically operate on regular schedules, giving you flexibility in choosing the departure time that suits your travel plans best. 

There are also overnight buses, so your-16 hour journey doesn’t take up a whole day of your vacation.

Tickets cost only USD 70-USD 96, and you can reserve your spot here today!

Medellín to Cartagena Luxury Bus Schedule

Departure TimeArrival TimeDurationPrice per Person
06:30 AM08:35 PM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
08:30 AM10:35 PM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
11:00 AM01:05 AM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
04:30 PM06:35 AM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
06:30 PM08:35 AM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
09:30 PM11:00 AM14 hours 5 minutesUSD 70Book Now 3 E1661788865313
06:30 PM08:35 AM16 hours 5 minutesUSD 96Book Now 3 E1661788865313
08:30 AM10:35 PM14 hours 5 minutesUSD 96Book Now 3 E1661788865313
11:00 AM01:05 AM14 hours 5 minutesUSD 96Book Now 3 E1661788865313
06:30 PM08:35 AM14 hours 5 minutesUSD 96Book Now 3 E1661788865313
09:30 PM11:00 AM14 hours 5 minutesUSD 96Book Now 3 E1661788865313
04:30 PM08:35 AM14 hours 5 minutesUSD 96Book Now 3 E1661788865313
Medellin To Cartagena1

2. Private Transfer from Medellín to Cartagena

Journey Duration: Custom Time

A private transfer is an excellent transportation option for those seeking a more personalized and convenient travel experience from Medellín to Cartagena!

A private transfer offers flexibility, privacy, and comfort and ensures a seamless journey tailored to your specific needs.

With a private transfer, you can say goodbye to the limitations of fixed departure schedules. Instead, you can choose your preferred departure time, allowing you to optimize your itinerary and make the most of your travel plans. 

Whether you wish to embark on an early morning adventure or prefer a later departure to savor the sights of Medellín a little longer, a private transfer can accommodate your schedule.

Traveling in a private vehicle provides exclusivity and privacy that other modes of transportation may not offer. 

Comfort is paramount during a private transfer, and you can expect a luxurious and spacious vehicle to transport you from Medellín to Cartagena. These vehicles are equipped with modern amenities to ensure a comfortable ride. 

While private transfers may be slightly more expensive than other transportation options, the convenience, flexibility, and personalized service they offer make them well worth the investment. 

So, if you’re looking for a hassle-free and tailor-made travel experience from Medellín to Cartagena, check out the options and book your trip online here!

Prices for a private transfer from Medellín to Cartagena:

  • Up to 2 passengers (SUV Car): USD 589
  • Up to 3 passengers (Standard Car): USD 213

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3. Flight from Medellín to Cartagena

Journey Duration: 1 hour 15 minutes

If you’re looking for the quickest and most efficient way to travel from Medellín to Cartagena, catching a flight is the way to go! 

With numerous daily flights connecting these two popular cities, flying offers convenience, time savings, and the opportunity to enjoy breathtaking aerial views of Colombia’s landscapes.

Several airlines operate regular flights between Medellín and Cartagena, providing a range of departure times throughout the day.

This flexibility allows you to choose a flight that best suits your schedule, whether you prefer an early morning departure or a more leisurely afternoon flight.

The flight duration from Medellín to Cartagena is approximately one hour, making it the fastest mode of transportation between the two cities.

By choosing to fly, you can save valuable time and maximize your stay in both Medellín and Cartagena.

Once you arrive in Cartagena, you’ll find that the airport is conveniently located near the city center, ensuring easy access to your accommodation or desired destinations.

Various transportation options, such as taxis and ride-sharing services, are readily available to take you to your final destination in Cartagena.

Tickets usually cost USD 71-USD 102, but we highly recommend comparing prices and booking in advance to secure the best deals!

Medellin To Cartagena2

4. Driving with Rental Car from Medellín to Cartagena

Journey Duration: ~12 hours

Renting a car is another excellent possibility for those seeking ultimate freedom and flexibility while traveling from Medellín to Cartagena. 

With a rental car at your disposal, you can embark on a self-guided road trip, explore hidden gems along the way, and enjoy the convenience of having your own vehicle throughout your journey.

Renting a car provides the freedom to set your own pace and itinerary. You can customize your travel experience, making stops at scenic viewpoints, charming towns, or natural attractions that catch your eye.

This flexibility allows you to immerse yourself in the diverse landscapes of Colombia, from the lush green mountains surrounding Medellín to the pristine beaches near Cartagena.

The journey from Medellín to Cartagena by car takes approximately 12 hours. While the drive may be longer compared to other transportation options, it offers the opportunity to witness the country’s beauty up close.

Before embarking on your road trip, it’s essential to familiarize yourself with the driving regulations and road conditions in Colombia.

Ensure you have a valid driver’s license, and consider obtaining an international driving permit if required.

Various car rental agencies are available in Medellín, offering a range of vehicles to suit your needs and preferences at an affordable price. 

Enjoy the freedom of the open road, savor the scenic beauty of Colombia, and create a personalized journey that perfectly suits your travel preferences!

Rentalcars compares 900 companies at over 53,000 locations. Click here to guarantee you the best car rental price.

Best day tours in Cartagena, Colombia

Get Your Guide helps you find the best tours wherever you are heading to. It’s usually the first website I check when I plan a trip to a new place.

The following widget shows some of the best tours in Cartagena, Colombia.

Frequently Asked Questions

What is the flight duration from Medellín to Cartagena?

The flight duration is approximately 1 hour and 15 minutes, making it the fastest mode of transportation between the two cities.

Are there any recommended coach bus or luxury bus operators for this route?

Some popular coach bus and luxury bus operators for the Medellín to Cartagena route include Rapido Ochoa and Expreso Brasilia. These companies are known for their reliable service and comfortable buses.

Can I rent a car in Medellín and drop it off in Cartagena?

Yes, many car rental companies offer the option to pick up a vehicle in Medellín and drop it off in Cartagena. However, it’s important to confirm this with the rental company.

Are there any tolls or road fees to consider when driving from Medellín to Cartagena?

Yes, there are tolls along the route between Medellín and Cartagena.

Is it necessary to have an international driving permit to rent a car in Colombia?

If your driver’s license is in a language other than Spanish, it’s recommended to have an international driving permit alongside your regular driver’s license.

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